Evidently, you can put time in a bottle.

Ristenza® is a fixed-dose combination specifically designed to help men last longer during sexual interactions and maintain a firm erection. Ristenza's® patented formula stands out as the true on-demand solution for Early Climax, while also including Sildenafil to enhance erection quality. Ristenza's® unique ingredients work synergistically, targeting eight receptors involved in the 'cascade effect' associated with ejaculation. This synergy allows for smaller doses of each ingredient, delivering targeted, safe, and proven effective results. Simply place one RDT on top of your tongue, and wait at least 30 minutes for maximum absorption before engaging in sexual interactions. Desired effects have been seen to last up to 6 hours.

Our API's combined provide a revolutionary method to combat Early Climax and ED in one convenient tablet. For more in depth questions on the dosage of each API or anything else you can think of feel free to contact our medical team by emailing support@ristenza.com.

Ristenza’s® patented formulation is crafted from three FDA-approved drugs, designed to work together synergistically to target the eight key receptors involved in ejaculation. This unique combination helps you gain more control over your experience while maintaining the same level of intimacy and connection with your partner. Ristenza® stands out as the premier, targeted therapy for Early Climax.

Before Ristenza®, the medical approaches to premature ejaculation were limited and often ineffective:

SSRIs (Antidepressants): While sometimes prescribed for PE, SSRIs are not specifically designed to treat it. They often require daily use and can come with a range of undesirable side effects.

PDE-5 Inhibitors (Erectile Dysfunction Medications): These drugs are FDA-approved to treat erectile dysfunction, but they do not address premature ejaculation or improve timing control.

Topical Gels/Creams: While these products can reduce sensitivity, they often result in a numbing effect that may lead to difficulty maintaining an erection and a diminished sense of pleasure. Application can also be messy, inconvenient, and may cause irritation or burning sensations.

Kegel Exercises: While these exercises can help strengthen pelvic muscles, they are not a proven solution for PE. On their own, they cannot provide the level of control and intimacy that Ristenza® offers.

Ristenza® goes beyond these traditional approaches by offering a proven, science-backed solution tailored specifically for premature ejaculation. With high levels of success reported by our users, Ristenza® empowers you to experience deeper intimacy and confidence in your relationship.

If you have any questions or concerns, feel free to reach out to us at support@ristenza.com. When you contact us, you’ll speak directly with a knowledgeable and understanding Ristenza® representative based in the United States. We respect your time and privacy—you won’t receive any spam emails from us.

We look forward to helping you take the next step toward greater intimacy and control.

Yes, Ristenza® is safe. Unlike daily medications, Ristenza® is taken on-demand, reducing overall exposure and minimizing the risk of side effects or dependency.

One of Ristenza’s® key ingredients, Tramadol, has a lower risk of addiction compared to traditional opioids. Numerous studies like the one in the National Institutes of Health’s PubMed Central, notes that the risk of addiction is significantly reduced when Tramadol is used intermittently and at appropriate doses (PMC3821202).

Because Ristenza® is only prescribed after an online consultation with a licensed physician, you can feel confident in its safety and effectiveness. If you have any concerns, our medical team is here to help.

Ristenza's® revolutionary formula operates by regulating the receptors responsible for delaying ejaculation, contributing to enhanced endurance during sexual activity. The key lies in the synergy of our three primary ingredients, each meticulously dosed for maximum efficacy. While these ingredients have demonstrated individual effectiveness in delaying ejaculation, higher doses often result in undesirable side effects. Ristenza® innovatively addresses this challenge by skillfully combining the three ingredients at significantly lower doses, ensuring effective outcomes without compromising safety. While we cannot guarantee extreme effectiveness for every single patient, we have seen extremely good results with both the RDT, and Pill formulations. In addition, we have not reported any side effects

For more scientific research, or questions please visit our clinical data tab, or email support@ristenza.com to be connected to our medical team who can explain in-depth the development, and effectiveness of Ristenza®.

Tramadol is a prescription analgesic that also modulates serotonin and norepinephrine pathways. In low, on-demand doses, it can help delay climax in some men by dampening the ejaculatory reflex and reducing hypersensitivity. It’s used in Ristenza® under physician oversight and should be taken exactly as prescribed.

When used together with sildenafil and dextromethorphan, the components may act synergistically—addressing arousal, sensitivity, and timing—to help reduce premature ejaculation for appropriate patients.

Safety note: Tramadol can cause drowsiness, nausea, or dizziness and may interact with medicines that affect serotonin (e.g., certain antidepressants). Do not use with alcohol or sedatives. Your clinician will confirm if it’s appropriate for you.

Dextromethorphan (DXM) is an FDA-approved cough suppressant found in many OTC products. At the low, on-demand dose used in Ristenza®, it also modulates brain pathways involved in timing and sensitivity—primarily through NMDA receptor antagonism and sigma-1 receptor effects. By dampening the central ejaculatory reflex.

Sildenafil (the active ingredient in Viagra®) is an FDA-approved PDE5 inhibitor that increases blood flow to the penis, helping you get and maintain a firmer erection. While sildenafil isn’t a PE drug by itself, improving erection quality can reduce the “rush-to-finish” cycle and performance anxiety that often worsen premature ejaculation. In Ristenza®, sildenafil supports arousal and firmness while tramadol and dextromethorphan help with timing and sensitivity, creating a complementary, on-demand approach.

Given that Ristenza® contains Sildenafil, which assists in achieving and maintaining an erection, it is recommended to skip your Sildenafil or Tadalafil on days you use Ristenza®. Ristenza® contains 42.2 MG of Sildenafil Citrate.

Ristenza® is compounded in the United States by a state-licensed compounding pharmacy. Our partner pharmacy maintains accreditations from URAC, ACHC-PCAB, and LegitScript, reflecting adherence to nationally recognized quality and safety standards.

Because Ristenza® is prepared specifically for each prescription, we do not publish the pharmacy’s details on the website. The dispensing pharmacy’s name, address, and contact information appear on your prescription label and receipt, as required by law.

• With dry hands, place one Ristenza® ODT/RDT on your tongue and let it fully dissolve (usually ~8 seconds). No water is needed—don’t chew or crush.

• Take 30–60 minutes before sexual activity. Many patients find a light/empty stomach helps it work faster; heavy or high-fat meals can delay onset.

• Avoid alcohol (can increase dizziness/sedation) and do not use nitrates or riociguat. If you take SSRIs/SNRIs, MAOIs, migraine meds, or other serotonergic drugs, use only under clinician guidance. All current medications are stated on medical intake form, and prescribing physician reviews before your online consultation.

• Keep tablets in the blister until use and store in a cool, dry place.

Prefer a swallowable pill?
On request (support@ristenza.com), Ristenza® can be compounded as a traditional tablet instead of ODT/RDT. Talk with your clinician—formulation can affect onset time and what’s right for you.

Effects can last up to 6-8 hours. Giving you the ability to be spontaneous whenever the moment strikes.

Shipping, tax and your doctor consultation are included in the price! What you see is what you pay.

We are happy to announce that Ristenza® is available now! You can click the order now page on this website to get started, or click here to choose your Ristenza® pack!

Once your online consultation is complete, your physician will begin the paperwork for your Ristenza® prescription—this usually takes around 1 day. From there, your prescription is submitted to our partner pharmacy, where it typically takes another 1 to 2 business days to compound and prepare your custom medication.

After that, your order is shipped via FedEx, with delivery typically within 5 business days—often sooner, depending on your location.

No, Ristenza® is a prescription medication specifically approved for individuals whose biological sex is male.

Women can place an order for Ristenza; however, the order must include their male partner's information. Additionally, he must be the one to complete the online consultation to receive a prescription.

If you have your online consultation, and decide you would not like to try Ristenza® or at any time prior to receiving your medication please email support@ristenza.com, and a full refund will be given!

But, due to state laws and pharmacy regulations governing prescription medications, we are unable to accept returns for Ristenza® once you have received your medication.

Simply click the refill link above, select which size of refill you would like, and enter you information! You will receive updates on the status of your refill.

Refills of Ristenza® do not require another doctor visit.

However, you are limited to a maximum of 16 tablets per 30 days.

Finally, Ristenza® can only be refilled up to 5 times within 6 months without another consultation.

The FDA does not verify the safety or effectiveness of compounded drugs. However, all three ingredients in Ristenza's® patented formula are FDA approved drugs and have a long history of use, safety, and effectiveness for their primary indications. Prescription products require a consultation with a healthcare provider.

Yes, you will need a prescription from a healthcare provider.

We are always open to speaking with new providers who are interested in offering Ristenza® to their patients. Please email us at info@ristenza.com.

Some of the possible effects include: nausea, gastro-intestinal disturbances, drowsiness, dizziness, constipation, headache, vomiting, pruritus/itchiness, agitation, diarrhea, dry mouth, sweating, skin flushing, dyspepsia, prolonged erection, nasal congestion, abnormal or blurred vision, abnormal hearing, decreased memory, Serotonin Syndrome.

If you experience a side effect not listed above please consult with prescribing physician.

You will receive text messages showing the status of your order.