Patents & Clinical Info

These three patents served as the basis for the development of the Ristenza^® formulation. You can access them through the links below.

On-demand use of tramadol, sildenafil, paroxetine and local anesthetics for the management of premature ejaculation: A randomized placebo-controlled clinical trial: (Click here to visit link)
Tramadol Use in Premature Ejaculation: Daily Versus Sporadic Treatment: (Click here to visit link)
Pharmacotherapy of premature ejaculation: a systematic review and network meta-analysis: (Click here to visit link)
Phosphodiesterase Type 5 Inhibitors for Premature Ejaculation: A Systematic Review and meta-analysis: (Click here to visit link)
Efficacy and safety of phosphodiesterase type 5 inhibitors on primary premature ejaculation in men: (Click here to visit link)
Tramadol for the Management of Premature Ejaculation: (Click here to visit link)
Safety and Efficacy of Tramadol Hydrochloride on Treatment of Premature Ejaculation: (Click here to visit link)
The Use of Tramadol “On-demand” for Premature Ejaculation: A Systematic Review: (Click here to visit link)
On-demand Tramadol Hydrochloride Use in Premature Ejaculation Treatment: (Click here to visit link)
Tramadol is an Effective Therapy for Mild to Severe Premature Ejaculation: (Click here to visit link)